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Texans 43, Jaguars 37
Andre Johnson caught a screen pass from Matt Schaub and ran 48 yards for the winning touchdown as Houston rallied to beat Jacksonville in overtime Sunday.
Schaub threw a career-high five touchdown passes, completed a franchise-record 43 passes and finished with 527 yards in the air, second most in NFL history. Warren Moon also threw for 527 yards for the Houston Oilers in December 1990 against Kansas City.
Norm Van Brocklin holds the record with 554 for the Rams in 1951.
Schaub completed his final 16 passes in regulation time to rally the Texans.
Johnson caught 14 passes for 273 yards, both career highs; the yardage was a team record. The Texans (9-1) won an overtime game for the first time at Reliant Stadium.
Chad Henne threw a career-high four touchdown passes in relief of injured Blaine Gabbert for the Jaguars (1-9). First-round pick Justin Blackmon finally had his breakout game, making seven catches for 236 yards. It was the first time in NFL history opposing players each had more than 200 yards receiving in the same game.
Falcons 23, Cardinals 19
Matt Ryan overcame a career-worst five interceptions, guiding Atlanta to its only offensive touchdown in the fourth quarter in a sloppy win.
The Falcons (9-1) turned it over a total of six times, but Michael Turner scored on a 1-yard run with 6:40 remaining to give Atlanta its first lead of the game. Ryan set up the score with four completions for 64 yards, including a 9-yarder to Tony Gonzalez on third-and-5 at the Arizona 10.
Coming off a bye, Arizona (4-6) lost its sixth straight game. The Cardinals tried to bolster their anemic offense by switching quarterbacks, replacing John Skelton with rookie Ryan Lindley, but Larry Fitzgerald couldn't hang on to a fourth-down pass after Ryan's fifth pick.
Packers 24, Lions 20
Aaron Rodgers threw two touchdown passes, including a 22-yarder to Randall Cobb with 1:55 left to lift Green Bay.
Mason Crosby made a 39-yard field goal with 19 seconds to go after missing two field goals earlier in the game.
Matthew Stafford couldn't put the Lions ahead on either of their last two drives in a game he'd like to forget.
Stafford threw two interceptions - one of which was returned 72 yards by Green Bay safety M.D. Jennings for a go-ahead score in the third quarter - and lost a fumble.
Green Bay (7-3) has won five straight and Detroit (4-6) has dropped two in a row.
Cowboys 23, Browns 20
Dan Bailey kicked a 38-yard field goal in overtime and Dallas overcame a critical fumble by Tony Romo that sparked a wild ending.
Bailey's winning kick with 6:07 remaining in OT came after both teams punted once in the first overtime game at Cowboys Stadium. Bailey hit a tying 32-yard field goal with 2 seconds left in regulation.
Dallas (5-5) rallied from a 13-0 halftime deficit and went ahead 17-13 on Romo's 28-yard pass to Dez Bryant.
A fumble by Browns rookie Brandon Weeden on a sack appeared to put the Cowboys in control, but Romo gave it right back with a fumble on another sack.
Buccaneers 27, Panthers 21
Josh Freeman threw a 15-yard touchdown pass to Dallas Clark in overtime to cap a comeback.
It was Freeman's third touchdown pass of the game for the Buccaneers (6-4).
Carolina appeared to have the game in hand after a 29-yard touchdown pass from Cam Newton to Brandon LaFell put the Panthers (2-8) up 21-10 with 4:34 left in the game. But after a 40-yard field goal by Connor Barth, the Panthers were forced to punt, and Freeman led the Bucs 80 yards on seven plays in 50 seconds with no timeouts.
He finished the drive with a 24-yard touchdown pass to Vincent Jackson between three defenders with 12 seconds left. Freeman went back to Jackson for a 2-point conversion on a slant route to send the game into overtime.
Saints 38, Raiders 17
Drew Brees threw three touchdown passes and Malcolm Jenkins returned an interception for another score to get the Saints back to .500.
Lance Moore caught two touchdown passes and Mark Ingram ran for a score as the Saints (5-5) won for the fifth time in six games and are in position to make a late-season playoff run despite the season-long distraction from the bounty scandal.
The Raiders (3-7) lost their third straight game under first-year coach Dennis Allen as their banged-up defense got picked apart by Brees' precision passing. Oakland has allowed 135 points in those defeats, the most in a three-game span for the franchise since allowing 141 in the first three games in 1961.
Brees finished 20 for 27 for 219 yards, extending his own records by throwing a touchdown in his 53rd straight game and completing 20 passes for the 46th straight game.
Broncos 30, Chargers 23
Peyton Manning threw for three touchdowns and Von Miller had three sacks to take the league lead with 13. Denver took a three-game lead in the AFC West by sweeping the Chargers.
Manning threw for 270 yards. He got off to a slow start, throwing an interception that Eric Weddle returned for a score and an early 7-0 lead. But the Broncos (7-3) took a 10-7 lead early in the second quarter and never trailed again.
Manning won his 148th regular-season game as a starting quarterback, tying John Elway for second on the all-time list. Brett Favre has 186.
The Chargers (4-6) lost for the fifth time in six games.
Redskins 31, Eagles 6
Robert Griffin III threw four touchdown passes, and Washington broke a three-game losing streak.
Griffin completed 14 of 15 passes for 200 yards and also ran 11 times for 85 yards. He threw for scores of 6, 49, 61 and 17 yards - one in each quarter.
Philadelphia's Nick Foles was 21 for 46 for 204 yards in his first NFL start, and his first two series ended with interceptions. Foles was starting in place of Michael Vick, who suffered a concussion in last week's loss to the Dallas Cowboys.
The Redskins improved to 4-6. The Eagles (3-7) have dropped six straight, accelerating the countdown toward the possible end of Andy Reid's 14-year tenure as coach.
Bengals 28, Chiefs 6
Andy Dalton threw for 230 yards and accounted for three touchdowns and A.J. Green caught a touchdown pass in his ninth straight game.
Green finished with six catches for 91 yards in another dazzling performance, Mohamed Sanu had a scoring grab and BenJarvus Green-Ellis ran for 101 yards and a touchdown as the Bengals (5-5) won their second straight following a four-game losing streak.
Cincinnati now plays its next four games against teams with losing records.
Jamaal Charles had 87 yards rushing for Kansas City (1-9), but that was the only highlight for a team that lost its seventh straight amid a quiet crowd at Arrowhead Stadium.