Broncos 42, Cowboys 17

Aqib Talib's 103-yard interception return for a touchdown with 53 seconds left was the final indignity for the Cowboys in Denver's blowout of Dallas and its vaunted offense on Sunday.

It was Talib's 10th pick-6, just two shy of Darren Woodson's NFL record.

"No. 10," relished Talib. "It's just mind-boggling."

Sort of like Denver's defensive dominance of Dallas and its vaunted offense.

Ezekiel Elliott had the worst game of his career with nine carries for 8 yards, Dallas managed just 40 yards rushing and one first down on the ground. The Cowboys (1-1) went 3-for-14 on third downs and failed three times on fourth down, looking nothing like the team that dominated the Giants in their opener.

"I want to emphasize today, this is not what we're about in my view," Cowboys owner Jerry Jones said. "I feel strongly about that. On the other hand, this is what Denver is about."

The only big blemish in Denver's fifth straight 2-0 start was the apparently serious injury to their top draft pick, left tackle Garett Bolles, who left the stadium on crutches and with a boot on his left foot after getting hurt in the third quarter.

With the stadium still rocking in the final minute, Talib stepped in front of Dez Bryant, who had earlier beaten him for a TD, snared Dak Prescott's fourth-down pass and raced up the Dallas' dejected sideline.

He slipped Cole Beasley's tackle and followed linebacker Brandon Marshall's beautiful block of Prescott into the south end zone, where he jumped into the stands, exhausted by enjoying every last bit of what he called "an all-around complete ballgame from the Broncos."

Trevor Siemian tied a career high with four touchdown passes in a game that included an hour-long lightning delay that did nothing to slow Denver's rolling offense.

"We knew they were sound in the secondary," Jones said. "We were a little taken aback by how well they did offensively. "They seemed to really have our number. There's no excuses here. Their quarterback played outstanding."

Elliott, who's playing while his appeal of a six-game suspension for domestic violence works its way through the courts, came into the game averaging 108 yards rushing per game and more than 5 yards a carry in his career.

"We just were getting dominated up front," said Elliott, whose previous worst game was a 51-yarder in his NFL debut against the Giants last year. "We couldn't get any movement off the ball."

The star in the backfield on this day was C.J. Anderson, who rushed for 118 yards and a score and also caught a TD pass.

Thanks in part to Von Miller, who had two sacks, the Cowboys lost for the sixth straight time to the Broncos.

Siemian threw scoring strikes of 10 and 6 yards to Emmanuel Sanders as the Broncos built a 21-10 halftime lead. The Cowboys were lucky to be that close after a first half in which they managed just five first downs, converted one third down and were outgained 246 yards to 97.

The only touchdown for Dallas came on a 3-yard drive after DeMarcus Lawrence's strip sack of Siemian after beating right tackle Menelik Watson. Bryant beat Talib for the score two plays after Maliek Collins scooped up the loose ball at the Denver 3.

The Cowboys began the day without their top cornerback, Orlando Scandrick, who broke his left hand last week, and they lost rookie Chidobe Awuzie (hamstring) and Nolan Carroll (concussion) in the first half.

Denver scored on its first drive when Siemian found Sanders for a 10-yard strike, and the Broncos were driving for another score but Brandon McManus pushed a 49-yarder wide right, his second miss in three attempts since signing his contract extension Monday.

The game was delayed by lightning for 62 minutes in the first quarter. The Cowboys were at midfield with 33 seconds left in the first quarter when the teams were told to head to their locker rooms and fans retreated to the concourses.

Broncos coach Vance Joseph said they turned off the air conditioning and turned on the TVs to watch some football during the delay.

Miller joked that they spent it dancing and playing games.

"Connect Four, we had some peanut butter and jelly sandwiches," Miller said. "We had a couple of rock-paper-scissors in there, turned on the music for a dance contest. ... Just came in, danced around."

Actually, Miller didn't even do any of his usual dances after his sacks, but he did raise his arms after ending his career-high five-game sackless streak, which came after he'd been flagged twice for jumping offside.

"You think he was getting antsy?" Joseph said.

Dolphins 19, Chargers 17

Cody Parkey hit his fourth field goal from 54 yards with 1:05 to play, and Miami rallied in the fourth quarter to spoil Los Angeles' home opener.

Younghoe Koo missed a 44-yard field goal attempt with 5 seconds left after Philip Rivers maneuvered the Chargers (0-2) into scoring range in the final minute before a crowd of 25,381 in their first home game since relocating to the Los Angeles area after 56 seasons in San Diego.

Jay Cutler passed for 230 yards and Jay Ajayi rushed for 122 in the delayed season opener for the Dolphins, who spent the past nine days in California after leaving South Florida early to avoid Hurricane Irma. Parkey did most of their scoring, connecting from 30, 28 and 35 yards before burying his longest kick in the waning moments.

Rivers passed for 331 yards, and Antonio Gates set an NFL record with his 112th touchdown reception as a tight end.

Rivers and the Chargers moved 54 yards in 52 seconds to set up Koo, whose potential tying field goal was blocked in Denver last week. The undrafted rookie kicker pushed this one barely right.

Kenny Stills caught a 29-yard TD pass in the third quarter from Cutler, who went 24 of 33 without an interception in his Dolphins debut.

Parkey's 35-yard field goal trimmed Los Angeles' lead to one point with 6:28 to play, and Miami's defense held. The Dolphins got the ball back with 3:02 left, and Cutler got them into position for another big kick from Parkey, the Jupiter, Florida, native claimed off waivers two weeks ago.

The Dolphins were well-rested after their home opener against Tampa Bay was postponed, leaving them to play their latest season opener since 1977.

The Chargers' latest last-minute loss dampened the festivities around a fresh start for the franchise, which brought five members of its inaugural 1960 Los Angeles Chargers to its temporary home at 27,000-seat StubHub Center, which was packed with a lively mix of fans.

Gates broke his tie with Tony Gonzalez on an 8-yard throw from Rivers in the third quarter. Melvin Gordon scored the Chargers' first touchdown in their new home from 1 yard in the second quarter to cap a 70-yard drive, but both teams struggled to put together sustained scoring marches.

Seahawks 12, 49ers 9

Russell Wilson avoided two potential sacks and found Paul Richardson in the front corner of the end zone for a 9-yard touchdown with 7:06 left.

It was an offensive nightmare as both teams had combined for 14 total quarters without a touchdown this season before the Seahawks finally broke the seal on the goal line. Wilson avoided Arik Armstead in the pocket and got his pass away before DeForest Buckner could pull him down. Seattle (1-1) snapped a streak of more than 112 minutes without a touchdown, despite missing on opportunities twice inside the 49ers' 10-yard line earlier in the game.

Wilson was erratic at times and magical at the end. He was 23 of 39 passing for 198 yards. He rushed for another 34 yards, 27 coming on the decisive scoring drive. Wilson was 4 of 5 on the drive and aided by a 20-yard pass interference penalty against Dontae Johnson.

Blair Walsh added field goals of 25 and 27 yards, but missed the extra point after Richardson's TD that could have given the Seahawks a four-point lead. The 49ers (0-2) only needed a field goal to tie but never got into position to have an opportunity.

San Francisco went three-and-out after the touchdown, punted and never got the ball back. Rookie Chris Carson rushed for 93 yards, including 58 yards in the fourth quarter.

Redskins 27, Rams 20

Kirk Cousins threw an 11-yard touchdown pass to Ryan Grant with 1:49 to play to give the Redskins the victory against their former assistant coach, Rams and rookie head coach Sean McVay.

Cousins capped the winning 70-yard drive by finding Grant in the front left corner of the end zone.

The Rams (1-1) had tied the game at 20 on Greg Zuerlein's 40-yard field goal with 7:16 to play. It was set up on a trick play, when punter Johnny Hekker completed a 28-yard pass to Josh Reynolds to the Washington 17. But two penalties stalled the drive and the Rams had to settle for the field goal.

Chris Thompson scored on runs of 61 and 7 yards for the Redskins (1-1).

Mason Foster sealed it with 1:37 to go by intercepting Jared Goff.

Chiefs 27, Eagles 20

Chiefs rookie Kareem Hunt reached the end zone twice, Travis Kelce took a shovel pass 15 yards for the go-ahead touchdown and Kansas City held on.

Kelce's touchdown catch with 6:25 left and Hunt's second TD scamper appeared to have put the game away.

But Carson Wentz hit Nelson Agholor for an answering score with 14 seconds left, and Trey Burton jumped on the onside kick a few seconds later to give the Eagles one last throw to the end zone.

Wentz unloaded from just inside the 50-yard line, but his pass fell incomplete as time expired.

Kelce finished with 103 yards through the air, highlighted by his somersaulting score. Hunt had 81 yards on the ground, building on a record-setting debut in which he piled up 246 yards from scrimmage in a season-opening victory in New England .

Alex Smith had 251 yards passing for the Chiefs (2-0). Cairo Santos was 2 for 2 on field goals.

Wentz finished with 333 yards and two touchdowns passing, despite facing relentless pressure all afternoon. The spunky quarterback also led the Eagles (1-1) with 55 yards rushing.

Cardinals 16, Colts 13

Carson Palmer's late rally got the Cardinals into overtime and Tyrann Mathieu's interception set up Phil Dawson for a 30-yard field goal to win it.

Dawson made the most of his second chance after pushing a 42-yarder wide right as regulation time expired.

Arizona (1-1) never led until the final play. It hasn't started 0-2 since 2005.

Coach Bruce Arians won his 42nd career game and tied Don Coryell for the second-most wins in Cardinals history on the same field he called home when he won his first NFL Coach of the Year award in 2012 as an interim for the ill Chuck Pagano.

Indy, 0-2 for the fourth consecutive year, thought it may have changed directions after switching quarterbacks. But newcomer Jacoby Brissett was picked off on the first offensive play of overtime.

Steelers 26, Vikings 9

Ben Roethlisberger threw a pair of first-half touchdown passes, Le'Veon Bell ran for 87 yards and the Steelers kept Minnesota in check.

Roethlisberger hit Martavis Bryant for a 27-yard score in the first quarter and flipped a shovel pass to JuJu Smith-Schuster that the rookie turned into a 4-yard score. Roethlisberger finished 23 of 35 for 243 yards and the two scores as the Steelers (2-0) improved to 10-1 in home openers under Mike Tomlin.

Minnesota (1-1) played without quarterback Sam Bradford, who sat out with a left knee injury. Case Keenum struggled to get anything going in Bradford's absence, throwing for 167 yards on 20 of 35 passing.

Vikings rookie Dalvin Cook ran for 64 yards, but Minnesota failed to generate any real momentum against Pittsburgh's rejuvenated defense.

Buccaneers 29, Bears 7

Jameis Winston threw for 204 yards and one touchdown, helping the Buccaneers return from an unscheduled bye week forced by Hurricane Irma.

The defense stymied former teammate Mike Glennon with four takeaways. Robert McClain returned one of the quarterback's two interceptions for a TD, and the Bucs didn't let the Bears into the end zone until Deonte Thompson scored on a 14-yard reception with 1:43 remaining.

The Bucs (1-0) dominated despite having a short week of practice following the massive storm that forced postponement of the team's scheduled season opener at Miami. Winston completed 18 of 30 passes without an interception. He threw a 13-yard TD pass to Mike Evans, who had seven catches for 93 yards.

Glennon, who signed with Chicago as a free agent last winter, was 31 of 45 for 301 yards and two interceptions in his return to Raymond James Stadium. The Bears (0-2) finished with 310 yards total offense, 1 yard less than a Bucs offense that hasn't had much work in the past month.

Ravens 24, Browns 10

Baltimore relentlessly harassed two Cleveland quarterbacks, Joe Flacco ramped up his production with a pair of touchdown passes and the Ravens breezed.

Building on their season-opening shutout at Cincinnati, the Ravens picked off four passes and forced a fumble, giving them 10 takeaways in two games.

Most of the defense's damage came against Browns rookie quarterback DeShone Kizer, who left with a migraine headache in the second quarter after four ineffective series: a three-and-out, a lost fumble, an interception and a punt.

The former Notre Dame starter was replaced by second-year pro Kevin Hogan, but returned in the third quarter with Baltimore up 21-10. On his second series back, Kizer moved the Browns to the Baltimore 7 before being picked off in the end zone by Lardarius Webb.

Brandon Carr's interception with 6:09 remaining all but sealed the victory.

Titans 37, Jaguars 16

Derrick Henry, Delanie Walker and Jalston Fowler each ran for touchdowns, and the Titans dominated the Jaguars.

The result was probably more indicative of what to expect from the AFC South rivals than what each showed in their season openers.

Henry finished with a career-high 92 yards on the ground for the Titans (1-1), including 87 in the final two quarters. Starting running back DeMarco Murray spent much of the second half standing on the sideline and wearing a baseball cap backward, seemingly uninjured. There was no need to risk him in this one, the third consecutive lopsided score in the series.

Marcus Mariota, returning to the place where he broke his right leg last December, completed 15 of 27 passes for 215 yards. He had a 32-yard touchdown pass to Jonnu Smith in the final quarter.

Jacksonville's home opener felt eerily similar to most of the team's performances the previous five years: Lackluster offense and mistakes all over the field for the Jaguars (1-1).

Panthers 9, Bills 3

Carolina's defense allowed only three points for the second straight week, and Graham Gano converted three field goals.

The Panthers (2-0) held Tyrod Taylor and LeSean McCoy in check all day, limiting the Bills (1-1) to 176 yards and 10 first downs. McCoy had 9 yards on 12 carries and Taylor had 125 yards passing. The Panthers had three sacks, two by Julius Peppers in his first home game since re-signing with them.

The Panthers needed a late stop to seal the win.

Buffalo rookie Zay Jones tried to make a diving catch on fourth-and-11, but couldn't haul in the pass at the Carolina 3 with 9 seconds remaining.

The Panthers have not allowed a touchdown in two games after beating San Francisco 23-3 in Week 1.

But they lost tight end Greg Olsen in the second quarter to a broken right foot. Olsen did not miss a game in his previous 10 pro seasons.