American League

Blue Jays 6, Orioles 5 (11)

Toronto bashed four home runs, then scored the decisive run without taking a swing.

Jim Johnson walked Maicer Izturis with the bases loaded in the 11th inning, and the Blue Jays beat the Orioles Wednesday to avert a three-game sweep and end Baltimore's run of consecutive extra-inning victories at 17.

"It would have been a tough game to lose. It was a big game to win," said Toronto manager John Gibbons, who was ejected in the ninth inning after his team blew a 5-2 lead in the seventh.

With two outs in the 11th, J.P. Arencibia and Munenori Kawaski singled before Johnson (1-2) hit Brett Lawrie with a pitch and issued a four-pitch walk to Izturis, the No. 9 hitter in the lineup.

"I just had a hard time throwing a strike," Johnson said. "Kind of lost feel, and obviously that's a terrible way to lose a game."

Izturis said: "I just tried to look for a pitch and drive it up the middle. But he threw high fastballs, so on 2-0 I tried to be patient and make him throw strikes."

That didn't happen, and the last-place Blue Jays got out of town with a much-needed win.

"When you are struggling as a team and you have a lead and it evaporates, it's hard," Gibbons said. "We haven't played great baseball, but we haven't been swept."

One night earlier, the Orioles won their 100th consecutive game when leading after the seventh inning. In this one, their streak of extra-inning wins — 16 of which came last year — came crashing to a halt. It was the longest run since the Pittsburgh Pirates won 21 straight in 1959-60.

"It's not something I dwell on," Orioles manager Buck Showalter said. "I know our guys don't. But I understand how it's noteworthy."

Esmil Rogers (1-1) pitched the 10th and Casey Janssen got three straight outs for his sixth save.

Nate McLouth had two hits, walked twice and scored three runs for the Orioles.

Baltimore missed a chance to win it in the 10th when Manny Machado was thrown out at the plate by left fielder Rajai Davis while trying to score from second on a single by J.J. Hardy.

The Blue Jays hit all four homers off Josh Stinson, who was called up from the minors earlier in the day to make his Baltimore debut. Stinson gave up only five hits in 5 2-3 innings, but those included a two-run drive by Arencibia and solo shots by Jose Bautista, Edwin Encarnacion and Davis.

In his previous 20 big league games, with the Mets in 2011 and Milwaukee last year, Stinson allowed only two homers in 22 1-3 innings.

He was optioned to Triple-A Norfolk after the game.

Toronto starter Brandon Morrow took a two-hitter and a 5-2 lead into the seventh, but the right-hander failed in his bid to earn his first win of the season.

With one out, Nolan Reimold walked and Ryan Flaherty chased Morrow with an RBI double. Aaron Loup got an out before yielding an RBI single to McLouth, who scored on a triple by Machado.

Morrow gave up three earned runs and three hits — all of them doubles — in 6 1-3 innings.

Gibbons didn't go the distance, either. He received his first ejection of the year after resuming an argument started by Lawrie over a called third strike.

The Orioles got a first-inning run when McLouth hit a leadoff double and scored on a two-out double by Adam Jones, who improved to 12 for 29 (.414) with 10 RBIs against Morrow.

Stinson retired the first four batters he faced before walking Melky Cabrera. Arencibia followed with a shot to center for his fifth home run in the last 10 games.

Davis made it 3-1 in the third with his first homer in 42 at-bats this season. The Orioles got an unearned run in the bottom half after a throwing error by Lawrie from third base.

Encarnacion hit his second homer in two games in the fourth, and Bautista connected in the sixth to make it 5-2.

Tigers 7, Royals 5

Jose Valverde returned to Detroit with a save and Victor Martinez drove in a pair of runs to help the Tigers beat the Royals.

Max Scherzer (2-0) got the win, allowing five runs in five innings, with three Tigers relievers finishing the game. Valverde, called up earlier in the day, returned to the Tigers with a perfect ninth inning. Valverde lost the closing role during the postseason and wasn't offered a contract, but signed a minor-league deal earlier this month and returned to Detroit after a short minor-league stint.

Wade Davis (2-1) took the loss, giving up seven runs — three earned — in 3 2-3 innings. Davis allowed eight hits and four walks while only getting 11 outs.

White Sox 3, Indians 2

Alex Rios hit a two-run homer and the White Sox beat the Indians to stop a four-game losing streak.

Jeff Keppinger had two hits and drove in a run for the White Sox, who earned a split of the rain-shortened series. Jose Quintana (2-0) was charged with two runs and four hits in five-plus innings.

Rios connected in the fifth, hitting a two-out drive to left on an 0-2 pitch from Zach McAllister (1-3). Rios leads the White Sox with six homers.

Astros 10, Mariners 3

Chris Carter, Ronny Cedeno and Brandon Laird homered, Lucas Harrell pitched seven innings, and the Astros beat the Mariners.

The Astros took two of three in the series, and four of their seven wins this season have come against the Mariners, their new AL West foe. Seattle and Miami are the only teams without a series win this season.

Carter hit a solo shot in the second, Cedeno belted a three-run shot in the fourth and Laird also connected for a three-run drive in Houston's five-run sixth.

Harrell (2-2) allowed a run and six hits.

Rangers 11, Angels 3

Nelson Cruz capped a nine-run fourth inning with a three-run homer, Lance Berkman had four RBIs and Texas helped Yu Darvish cruise to a victory over Los Angeles in the rubber game of the series.

Darvish (4-1) allowed three hits over six scoreless innings, struck out 11 and lowered his ERA to 1.65 after getting staked to an 11-0 lead. It was the right-hander's 11th double-digit strikeout performance in 34 major league starts.

Darvish, who did not allow a runner past first base, is 5-1 with a 3.83 ERA in eight starts against the AL West-rival Angels — whom he has faced more than any other team since coming over from Japan last season.

Michael Roth (1-1) threw 75 pitches over 3 1-3 innings in his first big league start, allowing five runs and six hits. The 23-year-old left-hander made four relief appearances earlier this season, allowing two runs over five innings and striking out seven of the 19 batters he faced. He was filling in for Tommy Hanson, who is on the bereavement list because of a death in the family.

National League

Cardinals 4, Nationals 2

Yadier Molina hit a two-run single off Stephen Strasburg during St. Louis' three-run first inning, and the Cardinals beat the Nationals to complete a sweep and give Washington's All-Star ace the only four-start losing streak of his young career.

Jaime Garcia (2-1) allowed a run on Bryce Harper's sixth-inning groundout, but otherwise added to the offensive struggles of the Nationals, who have lost six consecutive home games and nine of their last 12 overall to fall to 10-11.

Washington produced only four runs in the three-game set, a rematch of the 2012 NL division series won by St. Louis.

Needing to be nearly perfect given Washington's lack of offense, Strasburg (1-4) struggled through a 26-pitch, 12-minute first inning.

Strasburg, who hasn't won since opening day against Miami, settled down and threw 110 pitches over seven innings, giving up no other runs and a total of five hits, along with seven strikeouts.

Rockies 6, Braves 5 (12)

Wilin Rosario scored on Yorvit Torrealba's single to left in the 12th inning as Colorado rallied in the ninth to deny Atlanta's Tim Hudson his 200th career win.

Michael Cuddyer and Josh Rutledge homered for the Rockies, who ended a three-game skid behind one-hit pitching by the bullpen over the last six innings. Matt Belisle (1-1), the fourth reliever used by Colorado, pitched two perfect frames.

Rosario led off the 12th with a double to left off Luis Ayala (1-1). After Cuddyer was intentionally walked, Belisle struck out on a bunt attempt. Torrealba ripped a single to left, and Justin Upton's throw home was wide as Rosario slid in with the winning run.

Pirates 5, Phillies 3

Pinch hitter Brandon Inge hit a tiebreaking RBI single in the eighth inning and Pittsburgh rallied to beat Philadelphia.

Roy Halladay pitched six innings of one-hit ball and Chase Utley and Ryan Howard hit upper-deck solo homers off Wandy Rodriguez, but Mike Adams (1-2) couldn't protect an eighth-inning lead.

Pedro Alvarez hit a solo homer off Antonio Bastardo in the seventh and his RBI single in the fourth was the only hit off Halladay.

Vin Mazzaro (1-0) retired the four batters he faced to earn the win. Mark Melancon worked the eighth and Jason Grilli finished for his ninth save in nine tries.

Diamondbacks 3, Giants 2 (10)

Pinch hitter Will Nieves delivered a sacrifice fly in the 10th inning to lift Arizona to a victory over San Francisco.

Gerardo Parra and A.J. Pollack also drove in a run for the Diamondbacks, who beat the Giants in 11 innings Tuesday night. Didi Gregorius had two hits.

Arizona led 2-1 before Brandon Crawford hit a tying homer off David Hernandez (1-0) with one out in the ninth. Crawford also doubled home a run in the seventh and finished with three hits.

Matt Reynolds got three outs for his second save in as many days.

Chad Gaudin (0-1) worked 2-3 of an inning in taking the loss.

Reds 1, Cubs 0

Mat Latos retired the first 10 batters and 15 of the first 16 he faced and mostly spared an overworked bullpen, leading Cincinnati over Chicago.

Todd Frazier hit a long home run to provide all the scoring Latos would need. With one out in the sixth inning of a scoreless tie, Frazier blasted a 2-1 pitch from Jeff Samardzija (1-4) 480 feet to straightaway center field to increase his team-leading home run total to six.

Latos (1-0), the victim of two blown saves among his first four starts this season, allowed four hits and a walk with four strikeouts. Aroldis Chapman pitched the ninth for his fourth save.

Samardzija (1-4) allowed seven hits and three walks with eight strikeouts and a wild pitch.

Padres 2, Brewers 1

Edinson Volquez threw seven strong innings and Carlos Quentin hit his first home run of the season, helping San Diego snap Milwaukee's nine-game winning streak.

Volquez (1-3) allowed just five singles, struck out three and did not walk a batter, lowering his ERA from 8.84 to 6.39 as San Diego ended a five-game skid. It marked only the fourth time in 127 starts that Volquez did not walk a batter.

Estrada (2-1) pitched 6 1-3 innings, allowing two runs, one earned, with two walks and three strikeouts.

Huston Street worked the ninth for his third save in as many opportunities.