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Buccaneers 42, Raiders 32
The Tampa Bay Buccaneers turned to big-play rookie Doug Martin to pull away in the second half, yet still needed one key defensive play to hold off the Oakland Raiders.
Martin rushed for a franchise-record 251 yards and four touchdowns and Ahmad Black intercepted a Carson Palmer pass after Oakland had cut an 18-point deficit to three late in the fourth quarter as the Bucs won Sunday.
Martin, who was born in Oakland and went to high school in nearby Stockton, had a memorable homecoming for the Bucs (4-4) by scoring on runs of 1, 45, 67 and 70 yards as he gashed what had been an improved run defense for the Raiders (3-5) the past few weeks.
Martin, the 31st pick in April out of Boise State, became the first back since at least 1940 to score on three TD runs of at least 45 yards in one game, according to STATS LLC.
He finished 45 yards shy of tying Adrian Peterson's single game record of 296 set in his rookie season in 2007.
Colts 23, Dolphins 20
Andrew Luck broke the NFL's single-game rookie record by throwing for 433 yards in leading Indianapolis.
Luck was 30 of 48 with two TDs and broke Cam Newton's previous mark of 422 yards set last season. And it came on the day coach Chuck Pagano returned to Lucas Oil Stadium for the first time since being diagnosed with leukemia.
Indy (5-3) has won three straight.
Miami (4-4) got another strong performance from Ryan Tannehill, too. He went 22 of 38 for 290 yards with one TD.
The rookie quarterbacks traded jabs all day, but Luck's 36-yard TD pass to T.Y. Hilton gave Indy a 20-17 lead, and Adam Vinatieri's 43-yard field goal with 6:03 left broke a 20-20 tie.
Packers 31, Cardinals 17
Tom Crabtree had a 72-yard touchdown that was Green Bay's longest of the season, and Randall Cobb added two scoring catches.
The Packers (6-3) finished with a season-high 176 yards rushing on 39 carries, the first time in a month they've cracked the century mark.
James Jones also had a touchdown reception, and Green Bay goes into its bye week with a four-game winning streak.
The break comes at a good time for the Packers, who lost Clay Matthews, Jordy Nelson and Bryan Bulaga to injuries.
John Skelton was 23 of 46 for 306 yards, his most passing yardage since last December, but Arizona (4-5) lost its' fifth straight.
Texans 21, Bills 9
Matt Schaub threw two touchdown passes and Arian Foster ran for 111 yards against Buffalo's NFL-worst rushing defense.
Andre Johnson caught eight passes for 118 yards and Foster scored for the fifth straight game for Houston (7-1).
Mario Williams had a sack and five tackles in his return to Reliant Stadium after he signed with the Bills (3-5) in the offseason. The Texans made Williams the No. 1 pick in the 2006 draft and he's still Houston's career sacks leader (53).
Schaub won for the 10th time in 11 starts. He completed 19 of 27 passes for 268 yards.
Panthers 21, Redskins 13
Cam Newton completed 13 of 23 passes for 201 yards with a touchdown and ran eight times for 37 yards and a score as Carolina snapped a five-game losing streak.
The Panthers (2-6) were in desperate need of a win after a series of close defeats that had players questioning whether the team had any leadership. Newton responded with one of his best games of the season, including a 19-yard touchdown pass to Steve Smith and an 82-yard completion that set up a score.
Robert Griffin III was 23 for 39 for 215 yards, ran 11 times for 53 yards and was sacked four times as the Redskins lost their third straight and fell to 3-6.
Bears 51, Titans 20
Brian Urlacher became the latest Chicago defender to return an interception for a touchdown and Jay Cutler threw three TD passes to Brandon Marshall.
Cornerback Charles Tillman forced four fumbles and Chicago created five turnovers while winning its sixth in a row.
The Bears (7-1) scored a franchise-record 28 points in the first quarter. They took control by forcing three turnovers in the first 13 minutes and turning them into 14 points. Urlacher went 46 yards for his score.
Seahawks 30, Vikings 20
Marshawn Lynch ran for 124 yards and a touchdown, rookie QB Russell Wilson threw three first-half touchdowns, and Seattle overcame 182 yards rushing by Adrian Peterson.
The matchup between the top two rushers in the NFL - Peterson and Lynch - didn't disappoint with Peterson having his best game since 2008.
Broncos 31, Bengals 23
Peyton Manning overcame a pair of interceptions by throwing three touchdown passes.
Trindon Holliday also returned a kickoff a Broncos-record 105 yards for a touchdown.
Manning improved to 8-0 career against Cincinnati (3-5), which has lost four in a row for the first time in two years. This win didn't come so easily.
Ravens 25, Browns 15
Joe Flacco threw a 19-yard touchdown pass to Torrey Smith with 4:26 as Baltimore won its 11th straight game inside the AFC North.
Smith caught Flacco's strike and spun away from cornerback Joe Haden as the Ravens (6-2) beat the Browns (2-7) for the 10th consecutive time. It was also Baltimore's 15th straight win following a loss, and helped the Ravens shake off a 30-point loss to Houston two weeks ago.
Baltimore improved to 5-0 after a bye week under coach John Harbaugh, who is 10-0 in his career against Cleveland.
Phil Dawson kicked five field goals for the Browns.
Lions 31, Jaguars 14
Mikel Leshoure ran for three touchdowns, Calvin Johnson got involved early and Detroit turned in its most complete victory of the season.
Detroit built a three-score lead before halftime and coasted after the break. It was a much different feeling for the Lions (4-4), who trailed in the second half in each of their other wins.
Leshoure finished with 70 yards rushing and scored on runs of 7, 1 and 8 yards, becoming the first in franchise history to run for three touchdowns in the first half. Not even Hall of Famer Barry Sanders accomplished that feat.