New York — Rookies Brett Marshall and David Adams have a couple of keepsakes from this ugly loss to put on their shelves. Shortstop Alberto Gonzalez can at least tell his friends he got to pitch in the big leagues.

Phil Hughes, well, this one is going to stick with him for all the wrong reasons.

Hughes was knocked out in a seven-run first inning Wednesday night, giving up a grand slam to Raul Ibanez, and the New York Yankees went on to a 12-2 loss to the Seattle Mariners.

“You never want to put your guys in a position to have to go through a game like that,” Hughes said. “It was basically given away in the first inning. You’ve got guys playing out of position with a chance to get hurt and position players having to pitch. There’s nobody that feels worse about it than I do, and the next four days are tough for sure.”

The Mariners chased Hughes (2-3) after he got only two outs in the first. Trying to preserve his bullpen, Yankees manager Joe Girardi had Marshall throw 108 pitches in his big league debut, then brought in Gonzalez for the final out.

“He saved the bullpen is what he did for us,” Girardi said of Marshall’s 5 2-3 innings. “That’s not easy being a rookie, first time out there, and being asked to do that.”

Marshall followed Preston Claiborne to the mound. After getting Michael Saunders to fly out to center field for his first out, he called for the ball and had catcher Chris Stewart throw it into the dugout. Stewart knew to toss Marshall’s first strikeout ball to Girardi for safe keeping.

But all was not so smooth for the right-hander, who was called up Monday for the second game of a doubleheader in Cleveland. He gave up Ibanez’s second homer, a two-run shot in the fifth, and Kyle Seager’s three-run homer in the sixth.

He put his hands on his head after Seager’s drive, and received a visit to the mound from pitching coach Larry Rothschild.

Gonzalez, acquired last week from the Chicago Cubs, moved from shortstop to the mound with two outs in the ninth and runners on first and third. He retired Robert Andino on a routine flyball.

“We need one out,” Girardi said. “It’s not something I want to do, but for me to bring in another pitcher. I think it doesn’t make a lot of sense there.”

Girardi asked Gonzalez before the bottom of the ninth inning if he was OK pitching: “A shortstop usually has pretty good command of where he’s throwing the baseball, so I figured he’s the guy.”

Adams was making his big league debut, too. Called up on his 26th birthday, the third baseman made several nice plays in the field and singled in the sixth. That ball came out of play, too.

He’s not sure who will get the prize.

“Well, shoot, my mom and wife are probably going to fight over it,” he said. “I’ll give them some boxing gloves and see who wins.”

Every Seattle starter had at least one of its season-high 16 hits and Jesus Montero was the only starter who failed to score a run in the Mariners’ best output this year.

Ibanez has connected three times in the first two games of his return to the ballpark in which — last year at 40 years old — he electrified crowds in late September and October with several key homers in the Yankees’ run to the AL championship series.

This time, the cries of “Ra-uuul!” were replaced by boos for Hughes when Ibanez connected for his 11th career slam.

Kendrys Morales, Michael Morse and Michael Saunders each drove in a run in the highest-scoring first inning at the stadium that opened in 2009.

The first inning outburst made it easy for Japanese right-hander Hisashi Iwakuma (5-1), who came in with a 1.74 ERA. He gave up solo homers to Vernon Wells — his 10th — and Stewart in seven innings.

“Those were big gifts,” Iwakuma said through a translator of the run support.

After getting Saunders to lead off the game with a fly to left field on the second pitch of the game, nothing was easy for Hughes in the shortest start of his career.

Dustin Ackley walked and Seager singled before Morales had an RBI single. Morse followed with another RBI hit before Hughes walked Justin Smoak to load the bases ahead of Ibanez.

Former Yankees prospect Montero singled and, after a forceout, Saunders, the 10th batter of the inning, doubled in a run to make it 7-0 and chase Hughes. The right-hander never failed to make it out of the first in his 110 previous starts.

“When I tried to go to changeup, slider, curveball, it seemed like nothing was there,” Hughes said. “Nothing I could really go to to try and find a way out of it, and that’s what happens.”

Ibanez hit an opposite-field drive to left field in the fifth and Seager’s long ball came in the sixth to make it 12-2. With a chance for his first career three-homer game, Ibanez popped out foul in the sixth to Adams.

Ibanez flied out in the eighth.

•The Yankees designated 3B Chris Nelson for assignment. ... Ichiro Suzuki has not reached base in his last 20 plate appearances. ... Mariners manager Eric Wedge said LHP Felix Hernandez was “pretty sore this morning” but the ace should be fine after tweaking his back Tuesday night. Wedge said he doesn’t think there will be any alteration of his routine between starts.