Mets 4, Reds 3

Lucas Duda hit a pair of two-run homers only hours after the Mets gave him the starting job at first base, and New York beat Cincinnati Friday night behind Jenrry Mejia for its first victory of the season.

Replacement closer Jose Valverde struck out Jay Bruce with two on to end it, and the Mets avoided their first 0-4 start since opening with five consecutive losses in 2005.

The 24-year-old Mejia (1-0), who beat out Daisuke Matsuzaka for the final spot in the rotation, struck out a career-high eight in six innings. Flashing a sharp breaking ball, he allowed one run and four hits in a steady rain and mist.

Bruce homered and drove in three runs for the Reds, who had won six straight at Citi Field. Mike Leake (0-1) gave up five hits and three walks in 6 2-3 innings.

Mets left fielder Eric Young Jr. robbed Brandon Phillips of a home run, and backup catcher Anthony Recker threw out speedy pinch-runner Billy Hamilton trying to steal second for a big out in the eighth.

Tigers 10, Orioles 4

Miguel Cabrera homered in eighth inning for his 2,000th career hit, and Detroit rolled to a victory over Baltimore.

Cabrera also hit three singles. His two-run drive made him the ninth player to reach 2,000 hits before turning 31.

Former New London High School and UConn-Avery Point star Rajai Davis and Torii Hunter also homered for the Tigers. Drew Smyly (1-0) relieved Anibal Sanchez after a fourth-inning rain delay and pitched three scoreless innings.

Rays 8, Rangers 1

Sean Rodriguez homered and tied a career-high with four RBIs, Jake Odorizzi got his first major league win, and Tampa Bay routed Texas.

Rodriguez got a two-out RBI in the first when he was hit by a pitch with the bases loaded, and hit a three-run homer during the third that put the Rays up 4-0. He was back in the lineup after missing Thursday night's 7-2 win over Toronto for the birth of his son.

Odorizzi (1-0) allowed three hits in six innings in his seventh big league start and 10th game overall. Ryan Hanigan hit a three-run homer during the fifth for the Rays.

Marlins 8, Padres 2

Giancarlo Stanton hit a long home run to help lead Miami to a win over San Diego.

Jarrod Saltalamacchia had three hits and drove in two runs and Adeiny Hechavarria had a career-high four hits for the Marlins, who have won four of five to start the season.

Tom Koehler (1-0) pitched six innings, allowing two runs and Brad Hand pitched three scoreless innings for his first career save.

Phillies 7, Cubs 2

Chase Utley hit a two-run homer and an RBI single, helping Philadelphia beat Chicago in the opener of Wrigley Field's 100th anniversary season.

John Mayberry Jr. also had a two-run drive for his fourth career pinch-hit homer as Philadelphia bounced back after dropping the last two games of its opening series in Texas. Roberto Hernandez pitched into the sixth inning in his Phillies debut after signing a $4.5 million, one-year contract in the offseason.

Indians 7, Twins 2

Nick Swisher hit a two-run homer in the sixth inning, two batters after Yan Gomes connected for a solo shot, leading Clevelandto a home-opening win over Minnesota.

Swisher's homer off Mike Pelfrey (0-1) allowed the Indians to cap a day of pomp and pageantry as they celebrated Progressive Field's 20th anniversary. Before the sixth, the Indians had been shut out by Pelfrey and were in danger of disappointing a sellout crowd that stuck around following a 2-hour, 13-minute rain delay and plummeting temperatures.

Giants 8, Dodgers 4

Michael Morse keyed a six-run first inning with a two-run single, and San Francisco beat Los Angeles, spoiling a Dodgers' home opener played nearly two weeks after they began the season in Australia.

After retiring the first two batters, Hyun-Jin Ryu got pummeled for six runs while giving up six hits, including four in a row as the Giants batted around. They finished Ryu with two more runs in the second, extending their lead to 8-0.

Rockies 12, Diamondbacks 2

Charlie Blackmon tied a team record with six hits and drove in five runs, helping Colorado beat Arizona in its home opener.

Blackmon finished 6 for 6 with three doubles and a two-run homer. The only other Rockies player with six hits in a game was Andres Galarraga against Houston on July 3, 1995.

Braves 2, Nationals 1

Benefiting from the decision to overturn Ian Desmond's inside-the-park homer on replay review, Atlanta beat Washington, spoiling the Nationals' home opener and giving rookie manager Matt Williams his first loss.

Desmond's shot down the left-field line in the fifth inning, which appeared to tie the game at 1-all, was switched to a ground-rule double after a five-minute delay after Braves manager Fredi Gonzalez requested the review. Desmond was sent back to second base and wound up getting caught in a rundown while trying to steal.

Royals 7, White Sox 5

Alex Gordon drove in three runs and Jeremy Guthrie pitched effectively into the sixth inning as Kansas City beat Chicago in its home opener.

Gordon hit a bases-clearing double in the first inning and Guthrie allowed four runs on seven hits, four walks and a hit batter in 5 2-3 innings. Lorenzo Cain drove in two runs with a two-out fifth inning single that put Kansas City ahead 7-2.