Stonington — Two people were killed and one was seriously injured in a head-on collision in the southbound lanes of Interstate 95 just north of Exit 91 around 6:15 p.m. Saturday, according to state police.

Melvin Wells, 55, of Hamden and Larry A. Stallings Jr., 32, of Bristol, both died in the crash.

Police said Stallings was driving northbound in the southbound lanes of I-95 when his car, a 2007 Toyota Avalon Z, collided with a 2005 Dodge Ram, killing its driver, Wells.

Londeen Jamal Pisani, 29, of Waterbury, a passenger in the Ram, was transported by Stonington Ambulance to Lawrence + Memorial Hospital after sustaining serious injuries. Pisani was in serious condition Monday, according to the hospital.

Four vehicles and 10 people were involved in the crash.

Stonington police closed ramps onto the highway Sunday morning while state police investigated the accident. The highway remained closed until about 1:20 a.m., according to a tweet by the Department of Transportation.

Police did not release any details about how and where Stallings entered the southbound lanes of the highway.

Police said the accident remains under investigation. Anyone with information is asked to contact state police at (860) 848-6500.