“Hello, you have reached the United States of America. We’re sorry no one is here to take your call right now. We have taken leave of our senses and are unsure when they’ll return. Please try again in three-and-a-half years.”

If America had a voice-mail message to the world, this would be it. We are running an experiment in exploring the consequences of suddenly having the world’s most important power go absent without leave on the world stage.

Some of the signs of U.S. withdrawal have made international headlines. But some of the ways we are abandoning our leadership role are less visible. For example, few things are more directly associated with American leadership than our standing as a source of innovation, research, and scientific and technological expertise. Yet, President Donald Trump — who has struggled to successfully conceive or maintain many policy initiatives — has shown remarkable steadfastness in his campaign against science.

George W. Bush had the War on Terror. Donald Trump has the War on Truth.

In the past month, the last few scientists have exited the White House Office of Science and Technology Policy’s (OSTP) Science Division. The OSTP is staffed at approximately a third of the level it was during the Obama administration; President Trump has yet to name a head of the office. Last week, the State Department’s top science and technology adviser, Vaughan Turekian, resigned amid a swirl of rumors that Secretary of State Rex Tillerson was planning on shuttering his entire science and tech operation.

Last week, the Union of Concerned Scientists released a study on the track record of the administration during its first six months entitled “Sidelining Science from Day One.” The study condemns the Trump team for “eroding the ability of science, facts, and evidence to inform public policy decisions” and asserts “emerging patterns reveal tactics to diminish the role of science in our democracy.”

Speaking of the need for qualified scientists in top jobs, Arati Prabhakar, the former head of the Defense Advanced Research Projects Agency (DARPA), put it succinctly when she told me, “These positions demand deep expertise and thoughtful leadership. Anything less risks the future.”

Of course, it is not just science under siege. More broadly the administration attacks facts and evidence wherever they do not suit their policy views. All evidence-based communities are under attack — the intelligence community, law enforcement, think tanks and journalists. Attacks come in all forms — disregard for data, ad hominem attacks on the messengers and their motives, deflections and false analogies.

The opposite of knowledge is ignorance. But the willful disregard of knowledge — regardless of motive — is stupidity. That is because those who battle facts are at war with reality. It is an unwinnable proposition.

David Rothkopf is the author of “The Great Questions of Tomorrow.” He is a visiting professor of international and public affairs at Columbia University’s School of International and Public Affairs and a visiting scholar at the Carnegie Endowment for International Peace.