American League

Rays 10, Blue Jays 8

Evan Longoria homered during a five-run first inning against wild Francisco Liriano and Tampa Bay went on to outscore Toronto on Friday night.

Liriano faced only eight batters, walking four and giving up three hits before getting pulled. The Blue Jays rallied for a 7-6 lead, but Tampa Bay overtook them by scoring three times in the sixth inning, two on a double by Steven Souza Jr.

Brad Miller and Derek Norris also drove in two runs each for the Rays.

Xavier Cedeno (1-0) won despite giving up a bases-loaded walk to Troy Tulowitzki that put the Blue Jays ahead in the sixth. Alex Colome got four outs to earn his third save

J.P. Howell (0-1) took the loss.

Josh Donaldson and Tulowitzki hit their first home runs for Toronto.

The game started on time despite a late arrival by the umpiring crew. The four umps needed a police escort after a fire shut down a highway, and they got to Tropicana Field just 42 minutes before the first pitch.

The Rays’ five-run first included Daniel Robertson’s first major league hit, a single. Longoria connected for his second homer.

Tulowitzki drove in four runs. He hit a two-run double in the first off Matt Andriese.

Rangers 10, Athletics 5

Nomar Mazara hit his first grand slam and had a career-high six RBIs to lead the Texas Rangers over the Oakland Athletics for their first victory of the season.

Mazara is hitting .588 through four games, including 3 for 5 in this one. Rougned Odor hit his third homer of the season and had two hits. Texas was swept by Cleveland in its three-game opening series, also at home.

Alex Claudio (1-0) replaced starter A.J. Griffin in the fourth inning and held the A's to one hit over 3 2/3 scoreless innings. Griffin left with scrapes on his pitching palm and both knees after he slid on the warning track near the Oakland dugout trying to field an overthrow by Mazara from right field.

Raul Alcantara (0-1) allowed eight runs and four hits — including both homers — over two innings. He also hit a batter in his sixth big league start.

Royals 5, Astros 1

Jason Vargas got his first win in nearly two years and the Kansas City Royals beat the Houston Astros.

Kansas City got its first victory of the season after being swept at Minnesota in its first three games.

Vargas (1-0) returned from Tommy John surgery last September and earned his first victory Friday since June 8, 2015. He held Houston to a run and six hits and struck out six over six innings. The Royals entered 1 for 14 on the season with runners in scoring position then went 3 for 15 Friday, stranding 10 runners.

Mike Fiers (0-1) allowed two runs in six innings.

Twins 3, White Sox 1

Phil Hughes pitched six strong innings for his first win in almost a year and the Minnesota Twins beat the Chicago White Sox for their first 4-0 start since 1987.

Miguel Sano hit a go-ahead RBI double in the sixth, and Chris Gimenez added an RBI double in the seventh for the Twins, who led the majors with 103 losses last season after opening 0-9.

Hughes (1-0) made his first start since June 9, 2016, and allowed one run and five hits. The right-hander's season was cut short last year after he suffered a broken bone above his left knee and underwent surgery for thoracic outlet syndrome. Hughes last won in a rain-shortened game on April 18, 2016, against Milwaukee.

Tyler Duffey pitched two scoreless innings of relief, and Brandon Kintzler pitched a scoreless ninth for his second save.

Derek Holland (0-1) took the loss in his White Sox debut.

Angels 5, Mariners 1

Cameron Maybin and Kole Calhoun homered, and Jesse Chavez (1-0) pitched five-hit ball into the sixth inning of the Los Angeles Angels' victory over the Seattle Mariners.

Mike Trout drove in the first run amid numerous "M-V-P!" chants as the Angels snapped a four-game skid in home openers.

Nelson Cruz drove in the only run for the Mariners, who dropped to 1-4 on their season-opening road trip. Yovani Gallardo (0-1) yielded eight hits and three runs over five innings in his debut for Seattle.

National League

Brewers 2, Cubs 1 (11)

Ryan Braun scored from third base on a wild pitch in the 11th inning to give Milwaukee a win over Chicago.

Reliever Mike Montgomery (0-2) worked an 0-2 count on Manny Pina with one out before throwing a changeup that bounced past catcher Willson Contreras to the backstop. Contreras' throw home to Montgomery was late, and the Brewers celebrated by mobbing Braun at the plate.

Braun led off the inning with a single before moving to third after Jesus Aguilar walked and Jett Bandy was hit by a pitch.

Jared Hughes (1-0) pitched 1 2/3 innings of scoreless relief. The right-hander got a 4-6-3 double play to end a threat in the 10th after the Cubs put runners at first and second with one out.

Padres 7, Giants 6

Rookie Manuel Margot hit his first two big league homers and Yangervis Solarte had a go-ahead two-run double in the seventh inning, helping San Diego beat San Francisco in the Padres' home opener.

Solarte's double to the gap in right-center gave the Padres the lead again after the Giants had gone up 5-4 on Brandon Belt's first career grand slam with no outs in the sixth. Solarte had three hits and four RBIs.

San Francisco's bullpen troubles continued when George Kontos (0-1) walked Travis Jankowski opening the seventh and allowed a single to Wil Myers before Solarte doubled them in. Solarte advanced on a fly out and scored on Austin Hedges' sacrifice bunt to make it 7-5. That run came in handy because Belt homered again, off Ryan Buchter, to straightaway center with two outs in the eighth.

Jose Torres (1-0) pitched a perfect seventh for his first big league win. Brandon Maurer pitched a perfect ninth for his first save.

Pirates 5, Braves 4

David Freese and Francisco Cervelli hit back-to-back home runs and Pittsburgh won its home opener in snow flurries, beating Atlanta.

Freese and Cervelli went deep off reliever Josh Collmenter leading off the fifth inning. That gave Ivan Nova the cushion he would need at PNC Park, where the game time temperature was 37 degrees.

Nova (1-0) allowed just an unearned run over six innings in his first start since signing a three-year deal in the offseason to stay with the Pirates, who acquired him from the New York Yankees last summer. Tony Watson worked the ninth for his first save. Mike Foltynewicz (0-1) walked three in 3 2/3 innings to end a five-game winning streak dating to last season.

Rockies 2, Dodgers 1

Kyle Freeland allowed one run in six solid innings in his major league debut, leading hometown Colorado past Los Angeles.

The Denver native became the first starting pitcher to make his big league debut in his team’s home opener in the state in which he was born since 1966. Freeland (1-0) gave up four hits with a pair of walks and struck out six, including the first batter he faced, Logan Forsythe.

Colorado’s bullpen again came up big as Carlos Estevez and Scott Oberg each threw a scoreless inning before Jake McGee struck out the side in the ninth for his first save of the season. Hyun-Jin Ryu (0-1) was the loser.

Nationals 7, Phillies 6

Bryce Harper, Daniel Murphy and Jayson Werth hit homers to back Max Scherzer and Washington held on to spoil Philadelphia’s home opener.

Scherzer (1-0) allowed two runs and four hits, striking out seven in 6 2/3 innings. The NL Cy Young winner waited until the fourth game to pitch after a broken knuckle set him back in spring training.

Aaron Altherr hit a two-run homer off Sammy Solis in the seventh to get the Phillies to 7-4 and Freddy Galvis hit a two-run shot off Blake Treinen in the ninth. Vince Velasquez (0-1) struck out 10, but allowed four runs in four innings.

Reds 2, Cardinals 0

Amir Garrett pitched two-hit ball for six innings to win his major league debut, a sharp start for the former St. John's basketball player as Cincinnati beat St. Louis.

Garrett struck out four, walked two and needed only 78 pitches to record 18 outs. The 6-foot-5 lefty played two seasons of hoops for St. John's while already a Reds minor leaguer.

Michael Lorenzen and Raisel Iglesias combined for three innings of hitless relief. Iglesias went two innings to earn his second save.

Joey Votto hit an RBI double off Mike Leake (0-1), who went eight innings. Scott Schebler homered in the ninth.

Interleague

Diamondbacks 7, Indians 3

Paul Goldschmidt doubled in two during a five-run fifth inning and Arizona rallied from three down to beat Cleveland.

The Diamondbacks have come from behind in each of their four victories this season, three of those comebacks from three runs down. The Indians lost their first game after a three-game sweep at Texas earlier in the week.

Arizona got four runs in the fifth off Josh Tomlin (0-1) after a single and hit batter. Tomlin struck out the next two batters, but Goldschmidt lined a double into left-center field to give the Diamondbacks a 4-3 lead over the defending AL champions. Jake Lamb, who had two hits and scored twice, delivered an RBI single, ending Tomlin's night, and Yasmany Tomas greeted reliever Dan Otero with a double down the left-field line.

Shelby Miller (1-0) allowed three runs in 5 1/3 innings.