North Stonington — Ambulances from at least five towns responded to a two-car accident involving a vehicle going the wrong way on Interstate 95 north here on Wednesday night.

The crash was reported at 7:48 p.m., according to state police at Troop E in Montville, and involved "serious, life-threatening injuries."

It was not immediately clear how many people were involved or how many may have been injured.

Ambulances from numerous surrounding communities, including Stonington, Westerly, North Stonington, Groton and Ashaway, R.I., responded to the scene. Firefighters, including from Pawcatuck, also responded.

The crash scene was located about a mile north of the Exit 92 on-ramp. The northbound side of the highway was shut down between exits 92 and 93, and was expected to remain closed for a long period of time, state police said. Stopped cars and trucks were backed up for miles on the highway as of 9 p.m. Police started diverting vehicles backward off the northbound ramp at Exit 92 and onto Route 184 about 9:20 p.m., snarling traffic on that road.

The northbound on-ramp at Exit 93 remained open.

No further information was immediately available.

Day Staff Writer Jacinta Meyers contributed to this report.