New York - Only a few spots separate them in the seedings. Still, the considerable gulf between No. 1 Serena Williams and No. 4 Sara Errani was hard to ignore in their back-to-back matches Thursday at the U.S. Open.

Williams, seeking her 17th Grand Slam title and second straight at Flushing Meadows, brushed off an ungainly slide onto her backside en route to a typically easy second-round victory, 6-3, 6-0 over Galina Voskoboeva in half-full Arthur Ashe Stadium.

Barely worth talking about by Williams' standards: "I'll have to think about it and see what I can do better, but it was OK," she said.

Only an hour before on the same court, a much different scene: Errani imploded in a 6-3, 6-1 loss to her Italian teammate, 83rd-ranked Flavia Pennetta. Then, with tears welling in her eyes, Errani conceded that she's struggling to handle her high ranking and the high expectations that have come with that.

"My problem isn't that I lost. I've lost a million times in my life," Errani said. "My problem is trying to find the desire to fight and be on the court ready to fight. For a few weeks, I haven't felt like I wanted to be on the court. That's the problem."

That concession was the most unexpected development on Day 4 of the U.S. Open, where the tournament got back on track after a rainy Wednesday.

Among the results from Thursday's full slate:

• No. 4 seed David Ferrer overcame an error-filled second-set tiebreaker to top Roberto Bautista Agut 6-3, 6-7 (5), 6-1, 6-2.

• Second-seeded Victoria Azarenka defeated Aleksandra Wozniak of Canada 6-3, 6-1.

• Sixth-seeded Caroline Wozniacki beat Chanelle Scheepers 6-1, 6-2 to open the night session, with No. 2 Rafael Nadal playing the late match.

Williams got through her win unscathed, and when she was done in Ashe Stadium, five-time champion Roger Federer, the seventh seed, dispatched Carlos Berloq 6-3, 6-2, 6-1 in 1 hour, 35 minutes.

"It's one of those matches I expect myself to win if possible in straight sets and gain confidence in the process," Federer said. "All those things happened, so, yeah, I'm pleased about it."

American Christina McHale won a three-setter over Elina Svitolina, while another U.S. player, 81st-ranked Allison Riske, had an easier time in a 6-4, 6-2 victory over Mona Barthel.

"You never know at these things," Riske said after making the third round of her second straight Grand Slam tournament. "Anything can happen. That's kind of the beauty of tennis in general. Ranking is kind of just a number."

Victoria Duval, the 296th-ranked, 17-year-old American who earned her first victory in a Grand Slam tournament Tuesday, was also in action later.

The top U.S. man, No. 13 John Isner, had a late match. He was the last seeded American in the men's draw after No. 26 Sam Querrey lost in four sets to Adrian Mannarino. Another U.S. man, 20-year-old Jack Sock, moved to the third round with a 7-6 (3), 1-6, 7-5, 6-2 win over Maximo Gonzalez of Argentina.

Williams was pushed only briefly against Voskoboeva, ranked 77th.

Serving at game point trailing 5-3, Voskoboeva drew Williams to the net, and as Williams reached for the ball, her feet slid out from under her and she fell hard onto her backside, her racket slamming to the ground. Before she fell, however, she reached the shot to win the point. Two points later, she closed out the set.

The second set took all of 27 minutes. When it was over, Williams was sitting at the same table where Errani had cried earlier, being asked how she would advise the Italian, who said she was "destroyed by the pressure" of returning to the French Open this year, where she followed her 2012 appearance in the final with a run to the semifinals.

"I really wouldn't know what to say," Williams said. "I can only say that I think she's doing a good job. I mean, sometimes you have a tough day at the office."