American League

Astros 4, Royals 0

Dallas Keuchel probably could have thrown a second straight complete game on Tuesday night.

Houston Astros manager A.J. Hinch decided it would better not to overwork his ace.

Keuchel allowed seven hits in eight innings to lead the Astros to a win over Kansas City. His latest gem came after tossing a six-hit shutout in a victory over the New York Yankees in his previous start. Keuchel struck out seven and didn't walk a batter to lower his ERA to an American League-leading 2.03.

Pat Neshek allowed one hit in the ninth after Hinch decided to Keuchel (10-3) had done enough after throwing 106 pitches.

"I've got to balance the short term and the long term," Hinch said of pulling Keuchel. "We know he likes to finish games. The complete game shutout would have been cool for a lot of people but it's a tough call all the time. Most importantly we need to get through the game and get done, and have everybody feel good on the accumulation over the season."

George Springer had a two-run homer in the third inning. Jose Altuve drove in a run in the fifth to help Houston to the victory. The Astros have taken the first two games in a matchup of teams with the best records in the American League. Houston is 46-34 and Kansas City is 44-30.

Kansas City starter Danny Duffy (2-4) allowed six hits and four runs in 6 2-3 innings in his second start since returning from the disabled list.

Keuchel has been a workhorse for the Astros, working at least six innings in 28 straight games, the longest active streak in the majors.

Lorenzo Cain had three hits for Kansas City, including two doubles, but the rest of the lineup fizzled. The Royals produced more than one hit in only one inning while being shut out for the second time in a week.

"(Keuchel) utilized both sides of the plate really effectively," Kansas City manager Ned Yost said. "He'd get us looking away and then he'd start pounding us in. We couldn't gauge him. He was changing speeds. He really did a great job of keeping the ball down."

Keuchel got a little help from his defense when Springer robbed Omar Infante of a hit to center field. Springer raced and made an over-the-shoulder catch for the third out of the seventh inning.

"I was trying to force some early contact," Keuchel said. "I know they like to swing the bat and just tried to use it to my advantage."

Marwin Gonzalez singled with two outs in the third inning before Springer's soaring shot, which bounced off the foul pole in left field to make it 2-0 and snapped Springer out of an 0 for 8 slump.

Evan Gattis tripled with one out in the fourth inning. The fly ball sailed just out of reach of the glove of Cain, who raced up Tal's Hill in center to grab it and instead crashed to the ground and into the padded wall after coming up short.

"I felt like my first two steps were good and then after that my legs just gave out and into the wall I went," Cain said. "I gave a great effort but at the end of the day, the hill won."

Chris Carter walked on a wild pitch by Duffy, which sailed over catcher Drew Butera's head, and allowed Gattis to score and make it 3-0.

Springer drew a one-out walk in the fifth inning before scoring on a double by Altuve to push Houston's lead to 4-0.

Kansas City shortstop Alcides Escobar, who was scratched from Monday's game with a bruise on his index finger, went 1 for 4.

Rangers 8, Orioles 6

Mitch Moreland hit two home runs for the second straight game, and the Rangers celebrated the return of Josh Hamilton with a road win.

Shin-Soo Choo and Robinson Chirinos also went deep for the Rangers, who have hit eight home runs in the first two games of the series.

Moreland homered with a man on in the second and eighth innings. He leads Texas with 14 homers and ranks second with 43 RBIs.

Hamilton hit two singles and made a nice running catch of a sinking liner to left field in his eighth game of the season. The free-swinging slugger had been sidelined since May 31 with a strained left hamstring.

Chris Davis hit two home runs for Baltimore and Manny Machado added a solo shot. Miguel Gonzalez (6-5) got the loss.

Colby Lewis (8-3) improved to 4-0 in six starts since May 27. Shawn Tolleson earned his 11th save.

Indians 6, Rays 2

Danny Salazar pitched two-hit ball for 7 2/3 innings, and the Indians backed him with three home runs.

Jason Kipnis, Giovanny Urshela and David Murphy connected for Cleveland, sending Tampa Bay to its third straight loss.

Facing the Rays for the first time since losing in the 2013 AL wild-card game, Salazar (7-3) allowed one earned run and struck out two. He won for the first time in four starts.

Erasmo Ramirez (6-3) lost for the first time in six starts.

Interleague

White Sox 2, Cardinals 1 (11)

Chris Sale matched a major league record by striking out at least 10 in eight straight starts, and Chicago outlasted St. Louis on a home run by Tyler Flowers.

Sale struck out 12 in eight innings. The left-hander tied the mark set by Pedro Martinez in 1999 with Boston.

The White Sox ace had fanned every hitter in the St. Louis lineup by the end of the sixth. He is 0-2 with two no-decisions during the last four games of his streak, getting only four runs of support.

Sale helped himself in his 100th career start, singling for his first hit and scoring the first run for the White Sox.

Flowers hit his sixth homer with two outs in the 11th. He connected off Miguel Socolovich (2-1), pitching for the first time in nine days.

Daniel Webb (1-0) got the win and David Robertson earned his 16th save in 20 chances.

Pirates 5, Tigers 4 (14)

Neil Walker's RBI double in the 14th inning lifted Pittsburgh to the win.

The Pirates took the lead in that inning despite a massive baserunning mistake. With one out and a runner on first, Josh Harrison doubled, but Gorkys Hernandez retreated, thinking Rajai Davis had made a diving catch.

After being urged on by Harrison, Hernandez then broke for third, but didn't retouch second, and was out on a Tigers appeal. Walker followed with an RBI double off Tom Gorzelanny (2-1) to make it 5-4, but the Hernandez mistake cost the Pirates a run.

Ian Kinsler and Miguel Cabrera hit back-to-back singles with one out in the bottom of the inning, but Victor Martinez hit into a game-ending double play.

Deolis Guerra (1-0) picked up his first major league win with three scoreless innings.

Rockies 2, Athletics 1

Jorge De La Rosa pitched seven strong innings to carry Colorado past Oakland for its first interleague win of the season.

Charlie Blackmon singled to break a scoreless tie in the fifth. Nolan Arenado singled in the fourth to extend his major league-leading hitting streak to a career-high 17 games.

Troy Tulowitzki also singled and has hit in 14 straight for the Rockies, who snapped a three-game skid.

Colorado had been 0-7 in interleague games this season and had lost 14 straight in American League ballparks before De La Rosa and two relievers combined on a six-hitter.

The A's were without ace Sonny Gray, scratched from his scheduled start before the game because of illness.

Mariners 5, Padres 0

Rookie left-hander Mike Montgomery took a no-hit bid into the seventh inning and finished with a one-hitter for his second straight shutout as Seattle beat San Diego.

Making his sixth major league start, Montgomery opened the seventh by getting Justin Upton on a fly to left. Yangervis Solarte hit Montgomery's next pitch into the left-field corner for a double.

Until then, the closest the Padres came to getting a hit was Melvin Upton Jr.'s sinking liner to center, but Austin Jackson made a shoestring catch.

Montgomery, who turns 26 on Wednesday, was coming off his first career shutout, a five-hitter against Kansas City.

National League

Marlins 5, Giants 3

Major league batting leader Dee Gordon hit the first inside-the-park homer in the four-year history of Marlins Park, and the three-run shot helped Miami to the win.

Justin Bour also homered for the Marlins, giving a welcome jolt of power to a team without injured slugger Giancarlo Stanton.

Buster Posey hit his 12th homer for the Giants. He has 18 RBIs in his past 10 games.

Mat Latos (3-5) gave up three runs, two earned, in six innings for Miami. A.J. Ramos pitched a perfect ninth for his 11th save.

San Francisco's Ryan Vogelsong (6-6) allowed four runs in six innings.

Nationals 6, Braves 1

Jordan Zimmermann took a shutout into the eighth inning, and Washington continued its season-long dominance of the division rivalry.

The NL East-leading Nationals have won nine straight games in the season series with the Braves — including a three-game sweep at Washington last week.

Zimmermann (6-5) ended a streak of three losses since his last win on June 2. He allowed six hits in 7 2/3 innings.

Clint Robinson hit a two-run homer to cap Washington's four-run first inning off Shelby Miller (5-4).

Juan Uribe opened the ninth with a homer off former Braves reliever David Carpenter.

Brewers 4, Phillies 3

Aramis Ramirez drove in three runs and Ryan Braun had four hits, leading Milwaukee to the road win.

Hernan Perez had two hits, including a triple, for the Brewers, who have won six of eight. Neal Cotts (1-0) got the win, and Francisco Rodriguez earned his 17th save.

Carlos Ruiz homered for Philadelphia, which has lost five of six to drop its major league-worst record to 27-52.

Before the game, the Phillies said Pete Mackanin will remain their manager for the rest of the season. Mackanin took over on an interim basis last Friday after Ryne Sandberg resigned.

Ken Giles (3-2) got the loss in relief of Cole Hamels, who pitched seven solid innings.

Dodgers 6, Diamondbacks 4 (10)

Yasmani Grandal homered early and hit a two-run double in the 10th inning to finish with four RBIs, lifting Los Angeles to a victory over Arizona.

Howie Kendrick tied the game with a run-scoring single in the seventh and put the Dodgers ahead by hitting a homer on the second pitch of the 10th from David Hernandez (0-1). Grandal, who had a two-run shot in the second inning, made it 6-3 with his double into the corner in left.

Joel Peralta (2-1) pitched a perfect ninth inning and Kenley Jansen gave up a run-scoring double to Paul Goldschmidt in the 10th before closing out his 12th save.

Kendrick had four hits for the Dodgers, who have won eight of nine against Arizona.