East Hartford — After taking care of business in New England, Houston coach Dana Holgorsen decided to channel Bill Belichick, happy that his team can finally switch its focus to next weekend's American Athletic Conference championship game.

"Now, we're on to Cincinnati," he said.

Clayton Tune threw for 301 yards and four touchdowns Saturday as No. 19 Houston completed its regular season with a 45-17 win over UConn in cold and windy conditions.

Nathaniel Dell caught two touchdowns and Jake Herslow and Jeremy Singleton each topped 100 receiving yards to go with a TD apiece for Houston (11-1, 8-0 AAC), which plays at No. 4 Cincinnati for the conference title next Saturday.

"We knew we were going to be in this game, but yet we had to take care of business and play Memphis and then we had to take care of business and play at UConn," Holgorsen said. "That's tricky. Those are trap games and we didn't fall for it."

Freshman Alton McCaskill had a 31-yard touchdown run, his 16th of the year for the Cougars, but left the game in the second quarter holding his right shoulder. He finished with 54 yards on the ground.

The Cougars led 21-10 at halftime and scored on their first four possessions of the second half to put the game away.

Tune completed 20 of his 31 passes in three quarters of work.

"It's going to be cold up there (in Cincinnati) and that's something we're not used to," Tune said. "So, it's good to get out here and play in the cold and get used to it. I think we'll be ready for it next week."

UConn's Steven Krajewski had a 34-yard touchdown pass to Kevens Clercius before leaving the game in the second quarter with an injury. He was replaced by Micah Leon, who completed 10 of 13 passes for 62 yards for the Huskies (1-11) in interim coach Lou Spanos' final game.

Leon left with a leg injury with 2 minutes left. Jacob Drenn, a freshman walk-on, became the fifth UConn quarterback to see action this season.

Spanos, who took over in September following the retirement of Randy Edsall, will be replaced by Jim Mora, who was officially introduced as UConn's new head coach and begin his full duties on Sunday.

UConn has lost 14 consecutive games against FBS opponents and 36 of its last 37 such games.

The Cougars won all six of their away games this season, the fifth time in program history the team has been undefeated on the road, joining the 2011, 1988, 1979, and 1952 teams.

SACK AVENUE

Houston had seven sacks, bringing its season total to 43.

"That's ridiculous," said Logan Hall, who was credited with half a sack and also blocked a field goal in the first half. "Our 2s and 3s went out there and on their first or second play they knocked him down, so I'm really proud of how we performed."

STATS

Houston put up 472 yards of offense, including 323 in the air, while holding the Huskies to 238 yards.

INJURIES

McCaskill and Dell each left the game with injuries. Tune also got banged up, hitting his throwing hand on an opponent's face mask. But Holgorsen said he doesn't foresee any of them missing next week's title game.

"We will be as healthy as we've been all year," he said.

POLL IMPLICATIONS

Houston wasn't overly impressive, but a four-touchdown win solidified it as a Top-20 program going into a game with much bigger stakes.